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Peter Kleinebudde Continuous Manufacturing of Pharmaceuticals


A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.

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Сергей Сапцов Английский попроще. Времена глагола человеческим языком


Времена глагола в английском языке объясняются без использования словосочетаний: Present simple, Past simple, Future simple, Present perfect, Past perfect, Future perfect, Conditional, Conditional perfect, Present continuous, Past continuous, Future continuous, Present perfect continuous, Past perfect continuous, Future perfect continuous, Conditional continuous, Conditional perfect continuous, Passive voice.

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Mirmiran Majid Insertion of a Function


1-Insertion of a function belonging to a certain subclass of ${\bbb r}^x$}. 2-Insertion of a continuous function between two comparable precontinuous (semi-continuous) functions. 3-Strong insertion of a continuous function between two comparable precontinuous (semi-continuous )functions. 4-Insertion of a contra-continuous function. 5-Strong insertion of a contra-continuous function. 6-insertion of an $\alpha-$continuous function. 7-Insertion of a continuous function between two comparable $\alpha $continuous ($c-$continuous) functions.

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Татьяна Олива Моралес Future Perfect Continuous, Present Past Continuous. Построение, употребление, упражнения, тесты


В брошюре подробно рассматриваются времена группы Perfect Continuous (Future Perfect Continuous, Present Perfect Continuous, Past Perfect Continuous) на примерах и сигнальных словах. Пособие содержит упражнения и тесты для закрепления полученных навыков. Все упражнения и тест 1 адаптированы по методике © «Лингвистический Реаниматор», тест 2 имеет ключи. Пособие рекомендуется широкому кругу лиц, в том числе как самоучитель. Оно подойдет и начинающим, и тем, кто уже имеет определенные знания.

64 RUR

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Татьяна Олива Моралес Future Continuous, Present Continuous, Past Continuous. Построение, употребление, упражнения, тесты


В брошюре рассматриваются времена группы Continuous в английском языке (Future Continuous, Present Continuous, Past Continuous) на примерах и сигнальных словах для каждого времени. Пособие содержит упражнения и тесты для закрепления полученных навыков. Все упражнения и тест 1 адаптированы по методике © «Лингвистический Реаниматор», тест 2 имеет ключи. Пособие рекомендуется широкому кругу лиц, в том числе как самоучитель. Оно подойдет и начинающим, и тем, кто уже имеет определенные знания.

64 RUR

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Sir Charles Mackerras. Janacek: Operas (10 CD)


Треклист: 1. CD 1 Prelude - Peter Dvorsky2. Uz Se Vecer Chyli - Peter Dvorsky3. Co To Robis Mladku? - Peter Dvorsky4. Co Ty, Jenufo - Peter Dvorsky5. Dusa Moja, Stevo, Stevusko - Peter Dvorsky6. A Tak Bychom Sli Celym Zivotem - Peter Dvorsky7. Stevo, Stevo, Ja Vim - Peter Dvorsky8. Jak Razem Vsecko To Stevkovo Vypinani Schliplo - Peter Dvorsky9. Prelude - Peter Dvorsky10. Necham Jeste Dvere Otevreny - Peter Dvorsky11. Ba, Ta Tvoje Okenicka Uz Pres Dvacet Nedel - Peter Dvorsky12. Tetko Kostelnicko, Poslala Jste Cedulku - Peter Dvorsky13. Ale Videl Jsem Vchazet Sohaje - Peter Dvorsky14. CD 2 Co Chvila...co Chvila - Peter Dvorsky15. Mamicko, Mam Tezkou Hlavu - Peter Dvorsky16. Kdo To Je? - Peter Dvorsky17. Tot Zrovna Jde! - Peter Dvorsky18. Neni Ti Teskno, Jenufko? - Peter Dvorsky19. Dej Buh Stesti - Peter Dvorsky20. Vidis Laco, Ja To Tusila - Peter Dvorsky21. A Hen...uz Jsou Tu! - Peter Dvorsky22. To Bylo Nakeho - Peter Dvorsky23. Chud Atko! - Peter Dvorsky24. Jeste Jsem Tu Ja! - Peter Dvorsky25. Vstante, Pestounko Moja! - Peter Dvorsky26. Odesli - Peter Dvorsky27. Final Scene ('odesli' ) In The Orchestration By Karel Kovarovic - Peter Dvorsky28. Overture - Peter Dvorsky29. CD 3 Prelude - Helmut Froschauer30. Dostaneme Bourku - Helmut Froschauer31. Kmotrenka Zakoncertovala Si Take? - Helmut Froschauer32. Mami! - Helmut Froschauer33. Pantomime - Helmut Froschauer34. Change Of Scene - Helmut Froschauer35. To Cucis Lapakul!? - Helmut Froschauer36. Ze Nevis, Co Mame? - Helmut Frosc...

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Continuous Suction Vacuum Sealing Machine Sealer Seal Food LF1080A

Continuous Suction Vacuum Sealing Machine Sealer Seal Food LF1080A

Robert Mainardi L. Harnessing the Power of Continuous Auditing. Developing and Implementing a Practical Methodology


Written to help auditors jump start their organization's near real-time financial data monitoring and sharing capabilities, Harnessing the Power of Continuous Auditing provides step-by-step instruction on how to build, market, implement, and manage a successful continuous auditing program. Taking concept to reality, author and internal audit expert Robert L. Mainardi presents auditors, company executives, business unit managers, practitioners, and consultants with a complete road map to continuous auditing, from start to finish. Beginning with a thorough definition of the subject, Mainardi debunks the various myths surrounding the process?including the most common misperception that the internal audit department must have the corresponding automated technology to support it?and includes numerous documented proven techniques and instructions for more effective SOX work. A vital tool to enhance the auditor's skills and abilities, Harnessing the Power of Continuous Auditing's exhaustive coverage includes: The definition of continuous auditing Where to begin Methodology development Preparing for continuous auditing Root cause analysis Action plans Problem-solving tools Lessons learned Selling continuous auditing Conditions and challenges This all-in-one handbook of practical execution provides much-needed, accessible guidance on everything business professionals need to know to conduct and implement a successful continuous audit in their organizations.

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CY Photography Studio Continuous Lighting Kits 800W Video Red Head Light*3 with 200cm Light Stand*3 Photo Set

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Татьяна Олива Моралес Времена Past Continuous, Perfect Continuous в английском языке. Разница в употреблении, сигнальные слова, построение, правила, упражнения и тест с ключами


В брошюре рассматриваются времена Past Continuous и Past Perfect Continuous в английском языке; разница в их употреблении, построение и сигнальные слова на примерах для каждого времени. Пособие содержит упражнения и тест для закрепления полученных знаний. Все упражнения и тест адаптированы по методике © «Лингвистический Реаниматор», тест имеет ключи. Пособие рекомендуется широкому кругу лиц, в том числе как самоучитель. Оно подойдет и начинающим, и тем, кто уже имеет определенные знания.

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Татьяна Олива Моралес Времена Present Continuous, Perfect Continuous в английском языке. Разница в употреблении, построение, сигнальные слова, правила, упражнения, шпаргалки-тренажеры, тест с ключами


В брошюре подробно рассматриваются времена Present Continuous, Present Perfect Continuous, разница в их употреблении, сигнальные слова, построение. Пособие содержит упражнения, шпаргалки-тренажеры и тест для закрепления полученных навыков. Все упражнения адаптированы по методике © «Лингвистический Реаниматор», к тесту даны ключи (правильные ответы). Пособие рекомендуется широкому кругу лиц, в том числе как самоучитель. Оно подойдет и начинающим, и тем, кто уже имеет определенные знания.

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В. А. Державина Английский язык. Времена глаголов


В пособии рассматриваются английские времена группы Simple, Perfect и Continuous. Большое внимание уделено сравнению употребления времен, так как именно выбор временной формы часто вызывает трудности у изучающего английский язык. Сопоставляется употребление Present Simple и Present Continuous, Past Simple и Past Continuous, Present Perfect и Present Perfect Continuous, Past Simple и Present Perfect. Отдельно разбираются вспомогательные глаголы – to be, to have, to do. Большое количество упражнений помогает закрепить материал и постепенно достичь автоматизма в выборе времени. Издание предназначено для всех, кто учит английский язык.

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